Ethyl trifluoroacetate

Application Fields

Organic Synthesis Intermediates:

As a fluorine-containing building block, it participates in reactions such as Claisen condensation and Michael addition, and is used to synthesize ethyl trifluoroacetoacetate, fluorine-containing heterocyclic compounds (such as pyrazoles, pyrimidines), etc. These compounds are important precursors for pharmaceuticals and pesticides.

For example, in the synthesis of antifungal drugs and herbicides, the fluorine atom of ethyl trifluoroacetate can enhance the lipophilicity and biological activity of the molecule.

Solvent:

Due to its characteristics such as strong polarity, moderate boiling point (61℃), and good solubility for organic substances, it can be used as a special solvent for organic reactions or extraction processes.

Pharmaceutical and Pesticide Industries:

Used to synthesize fluorine-containing pharmaceutical intermediates (such as antiarrhythmic drugs, central nervous system inhibitors) and high-efficiency pesticides (such as fluorine-containing insecticides, fungicides). The introduction of fluorine atoms can significantly improve the selectivity and stability of drug efficacy.

CAS NO: 383-63-1

EC NO: 206-851-6

Molecular Formula: C₄H₅F₃O₂

Molecular Weight: 142.077709

Alias: Ethyl Trifluoroacetate;

Structure: